Hurley, whose only previous tournament loss was the 1990 title game when he was a freshman, capped his impressive career with a personal-best 32 points.
Jason Kidd and the rest of the California basketball team saw to that by upsetting the two-time defending national champions, 82-77, Saturday in the second round of the Midwest Regional.
While the Bears made the round of 16 for the first time since 1960, Duke failed to advance that far for the first time in eight years.
The Blue Devils (24-8) had been in the previous five Final Fours and six of the last seven. Before Saturday, Mike Krzyzewski had coached them to a 33-5 tournament record since 1986, including 18-1 in the 1990s.
Cal (21-8), which has won 11 of 12 games under the positive reinforcement of 29-year-old coach Todd Bozeman, will meet Kansas (27-6) in St. Louis on Thursday in the regional semifinals.
Kidd, Cal's phenomenal freshman, won a second consecutive game with a wild, one-handed layup.
Duke rallied from a 70-53 deficit to take a 77-76 lead with 2:21 to play. After neither team scored for more than a minute, Kidd tried to pass the ball inside and it was batted away.
But Kidd recovered the loose ball and, falling down after being fouled by Grant Hill, tossed a right-handed shot off the backboard and through the net. Kidd made the free throw for a 79-77 Cal lead.
Kidd, who had 11 points and 14 assists, added another free throw, and Lamond Murray, who scored 28 points on 11-for-17 shooting, hit two foul shots to seal Ca's eighth consecutive victory and hand Duke its first tournament loss since the 1990 final against Nevada Las Vegas.
In the opening-round game last Thursday, it was Kidd who beat Louisiana State with a high-banking layup with one second to play. LSU Coach Dale Brown, however, said the sixth-seeded Bears had no chance to beat the third-seeded, 10th-ranked Blue Devils and that Kidd would be no match for Bobby Hurley, Duke's All-American point guard.
At this point, I was 100% sure. There was no way Cal would win this game. Losing a 14 point halftime lead, then a late 4th quarter three point lead, and then blowing a chip shot field goal that would have won the game? You don't make these mistakes and beat a team like USC. It just doesn't happen. Even when Reggie Robertson threw a spectacular 25 yard laser touchdown into the outstretched hands of Jonathan Makonnen with two Trojan pass rushers bearing down on him, I didn't believe. And I really didn't believe when USC immediately responded with a quick score to send things to a 3rd OT.
I'm not even sure I believed after Ryan Killeen missed a 40 yard field goal after USC's possession was stymied with a poorly timed penalty. And when Cal failed to get a first down and get any closer for TFred I wasn't sure I could handle the pain of a 3rd failed attempt. When the field goal unit trotted onto the field the Mic Man (or was it Mic Chick Kate Troescher at the time? My addled brain doesn't remember) told us all to join our hands in a silent prayer to the Gods of Football. A part of me still believes that the well-timed display of desperate unity somehow made the difference, though TFred kicking one yard further back from the line of scrimmage may have had more to do with it. In any case, you all know what happened next. I was so overwhelmed by the victory that I was momentarily stunned, but I was quickly forced to regain my awareness or risk being trampled by the downward surge of 18-22 year old humanity that flowed onto the field in rapturous celebration of a wholly unexpected win for the ages.