As for winning it? Nope. I thought a healthy Oregon would have won last year, but the Ducks are not better this season while Ohio State clearly is. USC has the most raw talent, but their defense isn't ready to win two in a row against the nation's best. UCLA means you have to rely on Rosen. Arizona and ASU have their various quirks. It's going to take a really special team to upset the Buckeyes, and I don't think they're in the Best Coast this year.
Nik Jam: The Pac-12 always seems to beat each other up, but I have a feeling whoever wins the Pac-12 South, should they beat Oregon (or whoever) in the Pac-12 Championship Game, should make the playoff even with two losses.
PerryScope: I think USC will indeed make the Playoff finishing 11-1 (8-1) with a loss at Autzen Stadium to the ducks. However I do not see them winning it all. Ohio State, Alabama, and TCU are all better teams in my opinion and I think the lack of experience of players and coaches will hurt the Trojans in the long run.